P-235. Gonadal function after total body irradiation and allogenic marrow transplantation
نویسندگان
چکیده
منابع مشابه
Gonadal function after allogenic bone marrow transplantation for thalassaemia.
Thirty prepubertal patients with thalassaemia major (15 boys and 15 girls) aged from 9.3 to 17.2 years (mean 12.9) who had successfully undergone allogenic bone marrow transplantation were studied. Before the transplant all patients were given short courses of high doses of busulphan (total dose 14 mg/kg) followed by cyclophosphamide (total dose 200 mg/kg). Pituitary gonadal function was assess...
متن کاملAllogenic Stem Cell Transplantation and Total Body Irradiation
The clinical importance of bone marrow transplantation has increased considerably in recent decades. More than 450 centers for bone marrow transplantation now exist worldwide, performing more than 5000 transplantations per year. The number of transplant centers and patients has increased dramatically in Turkey in the last several years. When transplant donor and recipient are different individu...
متن کاملTotal-body irradiation for bone marrow transplantation.
Total-body irradiation (TBI), when given as part of bone marrow transplantation (BMT), works by enhancing immune suppression and by exerting a tumoricidal effect. The modality has been made less toxic because of new approaches to delivering TBI, such as fractionation, and partial organ shielding, Colleen Lawton, MD, professor at the Medical College of Wisconsin, Milwaukee, said at the 1998 Amer...
متن کاملLung function changes after allogenic bone marrow transplantation.
The lung function of 21 patients with leukaemia (11 with acute myeloid leukaemia, six with acute lymphatic leukaemia, four with chronic myeloid leukaemia) and of five with severe aplastic anaemia was tested before and after allogenic bone marrow transplantation. Vital capacity (VC) was lowered in patients with leukaemia before transplantation. VC and FEV1 fell significantly after transplantatio...
متن کاملALLOGENIC BONE MARROW TRANSPLANTATION IN APLASTIC ANEMIA
Eighteen patients, twelve men and six women, with aplastic anemia underwent allogenic bone marrow transplantation (BMT) from HLA-matched siblings during the period of 1990 to 1996. The conditioning regimen was cyclophosphamide with or without busulfan, depending on the cause of aplasia. Antilymphocyte globulin (ALG) and cyclosporine were used for rejection and acute GVHD prophylaxis, respe...
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ژورنال
عنوان ژورنال: Human Reproduction
سال: 1997
ISSN: 1460-2350,0268-1161
DOI: 10.1093/humrep/12.suppl_2.229